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  • Daniel E. Furst, Norman B. Gaylis, +17 authors Orrin M. Troum
  • Medicine
  • Annals of the rheumatic diseases
  • 2007 (First Published: 2 February 2007)
  • OBJECTIVE To incorporate a new trial design to examine clinical response, cytokine expression and joint imaging in patients with rheumatoid arthritis (RA) switching from etanercept to infliximabContinue Reading
  • Philip J Mease, Stanley Cohen, +6 authors Ariella Kelman
  • Medicine
  • The Journal of rheumatology
  • 2010 (First Published: 1 May 2010)
  • OBJECTIVE To assess the efficacy and safety of 1 versus 2 courses of rituximab over 48 weeks in patients with rheumatoid arthritis (RA). METHODS Adult patients taking methotrexate with a previousContinue Reading
  • Paul Emery, Philip J. Mease, +6 authors Helen Tyrrell
  • Medicine
  • Rheumatology
  • 2011 (First Published: 1 December 2011)
  • OBJECTIVE To assess the efficacy and safety profiles of two different rituximab retreatment regimens in patients with RA. METHODS Four hundred and ninety-three RA patients with an inadequateContinue Reading
  • Charles H. Pritchard, Maria Greenwald, +6 authors William G. Reiss
  • Medicine
  • BMC Musculoskeletal Disorders
  • 2014 (First Published: 1 December 2014)
  • BackgroundAs recommended in the current prescribing information, rituximab infusions in patients with rheumatoid arthritis (RA) take 4.25 hours for the first infusion and 3.25 hours for subsequentContinue Reading
    IntroductionMagnetic resonance imaging (MRI) is increasingly being used in clinical trials of rheumatoid arthritis (RA) because of its superiority over x-ray radiography (XR) in detecting andContinue Reading
  • Josef S. Smolen, Jonathan Kay, +10 authors Mittie K. Doyle
  • Medicine
  • 2013 (First Published: 1 June 2013)
  • Background GO-AFTER was the first multicenter, randomized, placebo (PBO)-controlled trial of the safety/efficacy of an anti-TNFα agent, GLM, in pts with active RA despite prior anti-TNFα therapy. Continue Reading