Noriko Naba

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Autocrine motility factor (AMF), a tumor-secreted cytokine, stimulates cell migration in vitro and metastasis in vivo. AMF is identical to the extracellular cytokines neuroleukin and maturation factor and, interestingly, to the intracellular enzyme phosphoglucose isomerase. The cytokine activity of AMF is inhibited by carbohydrate phosphate compounds as(More)
P.04.15.30 Acta Cryst. (2005). A61, C248 Crystal Structures of Autocrine Motility Factor Complexed with Inhibitors Ken-ichi Aoki, Nobutada Tanaka, Arayo Haga, Noriko Naba, Katsura Shiraiwa, Yoshio Kusakabe, Kazunori Hashimoto, Tatsuyoshi Funasaka, Hisamitsu Nagase, Avraham Raz, Kazuo T. Nakamura, School of Pharmaceutical Sciences, Showa University, Tokyo(More)
Mouse autocrine motility factor (mAMF), a tumour-secreted cytokine that stimulates cell migration in vitro and metastasis in vivo, has been crystallized by the hanging-drop vapour-diffusion method. The crystals belong to the monoclinic space group P2(1), with unit-cell parameters a = 69.97, b = 115.88, c = 73.27 A, beta = 101.76 degrees . There are two(More)
Introduction Aminoacyl-tRNA synthetases (aaRSs) play a central role in the assembly of amino acids into polypeptide chains. By selection of the correct amino acid for acylation of a specific tRNA, they provide the key for translation of the genetic code. The 20 aaRSs are divided into two classes of 10 enzymes each. TyrosyltRNA synthetase (TyrRS) is a class(More)
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