Noriaki Yoshimura

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Neurites in senile plaques in the cerebral cortex from an autopsied case of Alzheimer's disease were examined by electron microscope. Swollen axons containing vastly increased numbers of neurofilaments (NF) together with paired helical filaments (PHF) were common. In some of these axons the continuity of NF with PHF was frequently discernible. In one, there(More)
The olfactory bulbs and stalks were examined in a case of myotonic dystrophy that showed numerous Alzheimer's neurofibrillary changes (ANCs) in the brain. Typical ANCs were found in the cell body of many mitral cells and tufted cells and of a few outer and inner granule cells. In addition, massive ANCs were present in the anterior olfactory nucleus, where(More)
“Microrosette ependymoma,” which is ependymoma with numerous microrosettes throughout the tumor, has rarely been reported. We describe an autopsy case of cervical cord ependymoma with two unusual features: the presence of numerous microrosettes and the formation of trabecular architecture. The tumor originated in the C2 segment of a man aged 23 years and(More)
Argon laser photocoagulation was placed on the confluent monolayer of cultured chick retinal pigment epithelial cells as a model of the regeneration process of retinal pigment epithelium after laser burn. The intense fibrillar net immunofluorescent pattern of fibronectin appeared on the burnt area from 2 h after the laser application, before the beginning(More)
· Background: Our purpose was to analyze the expression of Fas antigen on CD4+ lymphocytes in the aqueous humor (AH) and cerebrospinal fluid (CSF) of patients with Vogt-Koyanagi-Harada disease (VKH). · Methods: Using three-color flow cytometry, we assessed T-lymphocyte subsets stained with fluorescence-conjugated anti-CD3, CD4, CD8, CD29, CD45RA, CD45RO,(More)
Subretinal strands in proliferative vitreoretinopathy removed during vitreous surgery in ten cases were studied histologically; tissue culture was taken from five of the ten cases to obtain more material for investigation. Tissue culture was successful in all five cases. The cultured tissue just next to the original strand preserved the characteristics of(More)
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