Noriaki Hashimoto

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OBJECTIVE The image quality in whole slide imaging (WSI) is one of the most important issues for the practical use of WSI scanners. In this paper, we proposed an image quality evaluation method for scanned slide images in which no reference image is required. METHODS While most of the conventional methods for no-reference evaluation only deal with one(More)
BACKGROUND Color consistency in histology images is still an issue in digital pathology. Different imaging systems reproduced the colors of a histological slide differently. MATERIALS AND METHODS Color correction was implemented using the color information of the nine color patches of a color calibration slide. The inherent spectral colors of these(More)
Cancer stem cells (CSCs) are thought to play important roles in therapy-resistance. In this study, we induced cancer stem-like cells from hepatocellular carcinoma (HCC) cell lines using a unique medium, and examined their potential for resistance to anti-cancer drugs. The human HCC cell lines SK-HEP-1 (SK), HLE, Hep 3B, and HuH-7 were used to induce cancer(More)
High-resolution 3D histology image reconstruction of the whole brain organ starts from reconstructing the high-resolution 2D histology images of a brain slice. In this paper, we introduced a method to automatically align the histology images of thin tissue sections cut from the multiple paraffin-embedded tissue blocks of a brain slice. For this method, we(More)
Color enhancement of multispectral images is useful to visualize the image's spectral features. Previously, a color enhancement method, which enhances the feature of a specified spectral band without changing the average color distribution, was proposed. However, sometimes the enhanced features are indiscernible or invisible, especially when the enhanced(More)
This paper proposes an encryption method that uses short keys to enable hierarchical access controls for JPEG 2000 codestreams. The proposed method provides images of various quality levels that may be different from the quality at encoding, though it uses a single codestream and a single managed key (masterkey). Only one key generated from the masterkey is(More)
The aim of this study was to develop an accurate predictive system for prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy. We pooled data of clinicopathological features of 234 HCC patients who underwent curative hepatectomy. On the basis of the pooled data, we established a simple predictive staging system (PS score) scored by the(More)
PURPOSE For realizing computer-aided diagnosis (CAD) of computed tomography (CT) images, many pattern recognition methods have been applied to automatic classification of normal and abnormal opacities; however, for the learning of accurate classifier, a large number of images with correct labels are necessary. It is a very time-consuming and impractical(More)
Computed tomography (CT) and magnetic resonance (MR) imaging have been widely used for visualizing the inside of the human body. However, in many cases, pathological diagnosis is conducted through a biopsy or resection of an organ to evaluate the condition of tissues as definitive diagnosis. To provide more advanced information onto CT or MR image, it is(More)