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— Intercell interference coordination (ICIC) in orthogonal frequency division multiple access (OFDMA) networks in general and in the 3GPP Long Term Evolution system in particular has received much attention both from the academia and the standardization communities. Understanding the trade-offs associated with ICIC mechanisms is important, because it helps(More)
—While intercell interference coordination (ICIC) for the downlink of multi-cell systems in general and orthogonal frequency division multiple access (OFDMA) networks in particular has been extensively studied, the uplink has received less attention. For uplink, the impact of ICIC on the overall system throughput (" the ICIC gain ") must be analyzed in a(More)
Device-to-device (D2D) communications underlaying a cellular infrastructure has recently been proposed as a means of increasing the resource utilization, improving the user throughput and extending the battery lifetime of user equipments. In this paper we propose a new distributed power control algorithm that iteratively determines the(More)
In this article we present arguments that the "antidiabetic" drug metformin could be useful as an add-on therapy to methotrexate for the treatment of psoriasis and, perhaps, for rheumatoid arthritis as well. Biochemical data suggest that both drugs may share a common cellular target, the AMP-activated protein kinase (AMPK). This enzyme is a master regulator(More)
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