Norbert Papst

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Electroretinograms (P-ERG) and cortical potentials (P-VECP) evoked by checkerboard patterns were examined in patients with defects of the ganglion cell and nerve fiber layers due to glaucoma. Only a few patients exhibited a prolonged latency in the P-VECP, whereas in the P-ERG all patients with papillary and visual field defects revealed a significantly(More)
Electroretinographic responses to pattern-reversal stimuli (P-ERG) were recorded in eight patients with protracted elevation of intraocular pressure. Pressures of bigger than 30 mm Hg result in marked amplitude reductions in the P-ERG. The observed changes probably reflect the impaired function of retinal ganglion cells caused by decreased oxygen supply.
Vascular autoregulation maintains stable retinal function in vivo in the face of changes in arterial pO2. We observed autoregulatory changes in the flow of perfusate through the isolated cat eye in response to changes in pO2. Hydrostatic perfusion pressure and all other variables of the perfusate, except for pO2, were kept constant. Throughout the(More)
The authors report on clinical and electrophysiological studies of a patient with Type I Oguchi's disease. Numerous small pigmentations of the retinal pigment epithelium (RPE) causing focal disruption of the Oguchi reflex were observed, a phenomenon which has not previously been reported. Consistent with reports of pathologic changes in the RPE, an abnormal(More)
Electroretinography can provide meaningful evidence of oculotoxic changes. We describe a new recording system specially constructed for animal experiments. It meets the standards for electroretinographical investigations and recording systems set up by international committees. The recording apparatus has a resolution of 0.49 microV (amplitude) and 1 ms(More)
PURPOSE The G1-TOP program is a short automated perimetric strategy which sub-divides the G1 grid of 59 points into four sub-grids. Each point is tested only once, but each patient's response is used to modify that particular point and the surrounding ones from the remaining sub-grids. This study compared the results of the G1-TOP program with the Standard(More)
Electroretinographical responses to brightness (H-ERG, Ganzfeld illumination) and pattern reversal (M-ERG, illuminating an area of 20 degrees) were recorded in two cases of occlusion of the temporal inferior branch of the retinal artery. While the H-ERG exhibited essentially normal responses, the M-ERG was markedly disturbed. With central fixation the(More)
The semisynthetic third generation cephalosporin cefmenoxime was injected through the pars plana into the mid-vitreous in seven rabbit eyes. The drug dosage varied between 0.5 and 15 mg. Seven control eyes were injected only with 0.9% NaCl-solution. Electroretinography was performed before injection and 1 week post injection. The rabbits were anesthetized(More)