Norbert Brau

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Objectives We undertook this study to determine if treatment candidacy and outcomes were similar between elderly and non-elderly patients. Methods This was a prospective cohort study that screened 4,025 patients with chronic hepatitis C for HCV antiviral treatment at 24 Veterans Affairs Medical Centers throughout the country. We used multivariable logistic(More)
Anaemia during peginterferon (PEG-IFN) and ribavirin (RBV) therapy is common in human immunodeficiency virus/hepatitis C virus (HIV/HCV)-coinfected patients despite the use of lower doses of RBV than are recommended for HIV-seronegative persons. In addition, concurrent zidovudine (ZDV) may exacerbate the anaemia caused by PEG-IFN and RBV. We retrospectively(More)
BACKGROUND/GOALS Many patients with a history of injection drug use (IDU) are excluded from hepatitis C virus (HCV) treatment. This prospective multicenter study aimed to determine the impact of IDU history on HCV treatment candidacy and outcomes. STUDY Between 1999 and 2001, 4318 HCV-infected patients seen at 24 VA Medical Centers were evaluated for HCV(More)
As the era of interferon-alpha (IFN)-based therapy for hepatitis C ends, long-term treatment outcomes are now being evaluated. To more fully understand the natural history of hepatitis C infection by following a multisite cohort of patients. Patients with chronic HCV were prospectively enrolled in 1999–2000 from 11 VA medical centers and followed through(More)
The editorial team of Digestive Diseases and Sciences (DDS) wishes to acknowledge the critically important role played by the individuals whose names appear in the following list of reviewers for calendar year 2009. Manuscript reviews by these clinical and research scientists, as well as by members of the editorial board, are the cornerstone of the journal(More)
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