Nora Luethi

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Acute partial transverse myelitis (APTM) may be the first clinical manifestation of multiple sclerosis (MS), of relapsing myelitis, or remain a monophasic event. Identification of risk factors associated with relapse or conversion to MS is important, as prognostic information might help to guide management. The objective of this study was to define(More)
STUDY DESIGN Retrospective 9-year survey. OBJECTIVES Clinical presentation of acute myelitis syndromes is variable, and neuroimaging and laboratory findings are not specific enough to establish the diagnosis with certainty. We evaluated the spectrum clinical features and paraclinical findings encountered during diagnostic workup and aiding the diagnosis.(More)
BACKGROUND Normal saline (NS) is the most commonly used crystalloid solution worldwide but contains an excess of chloride and may cause metabolic acidosis and hyperchloraemia. Such abnormalities may be attenuated by the use of a balanced solution such as Plasma-Lyte 148 (PL-148). OBJECTIVE To assess the feasibility, safety and biochemical and(More)
BACKGROUND The cardiac output (CO) response to sepsis is typically measured in the intensive care unit after modification by fluid and/or vasoactive drug resuscitation and found to be hyperdynamic. In contrast, the native (preresuscitation) CO in human sepsis is poorly defined. DESIGN AND DATA SOURCES Systematic literature review of studies reporting the(More)
OBJECTIVES Glycated hemoglobin A1c is used to estimate glycemic control. However, its value upon ICU admission may be altered by critical illness and not reflect true glycemic status. We assessed the relationship between ICU admission glycated hemoglobin A1c and premorbid glycated hemoglobin A1c levels. DESIGN Retrospective observational cohort study. (More)
BACKGROUND It is uncertain whether liberal glucose control in critically ill diabetic patients leads to increased ketone production and ketoacidosis. Therefore, we aimed to assess the prevalence of ketosis, ketonuria and ketoacidosis in critically ill diabetic patients treated in accordance with a liberal glycemic control protocol. METHODS We performed a(More)
OBJECTIVE The epidemiology of patients admitted to the intensive care unit after a drug overdose (OD) is poorly defined. We aimed to study the incidence, characteristics and outcomes of patients admitted to the ICU because of OD in Australia and New Zealand. DESIGN, SETTING AND PATIENTS Retrospective study of data from the Australian and New Zealand(More)
OBJECTIVE To assess the physiological, biochemical and haemodynamic response to a single intravenous (IV) dose of frusemide in critically patients. DESIGN, SETTING AND PATIENTS A prospective observational study of 21 critically ill patients in a tertiary intensive care unit in Australia. INTERVENTIONS We collected information on urine output (UO), fluid(More)
award winning session A460<lb>Pre-hospital emergency anaesthesia in awake hypotensive trauma<lb>patients: life saving or detrimental?<lb>K. Crewdson, M. Rehn, A. Weaver, K. Brohi, D. Lockey London's Air Ambulance, Pre-hospital Emergency Medicine, London, UK<lb>Correspondence: K. Crewdson London's Air Ambulance, Pre-hospital Emergency Medicine, London,(More)