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BACKGROUND A single nucleotide polymorphism (SNP) within MIR137, the host gene for miR-137, has been identified repeatedly as a risk factor for schizophrenia. Previous genetic pathway analyses suggest that potential targets of this microRNA (miRNA) are also highly enriched in schizophrenia-relevant biological pathways, including those involved in nervous… (More)
We describe in this paper the preparation of 46 new sugar nitrone derivatives and their antibacterial activity against Escherichia coli and Bacillus subtilis.
The synthesis and the interaction with brain receptors of some 2-carboxy-5-isopropenylcyclopentaneacetic acids, C-analogues of kainic acids, are reported. They do not displace kainic acid at cortical or striatal receptors.