Noppamars Wongwitdecha

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Impaired learning has been shown as a consequence of isolation-rearing in a variety of paradigms. However, there are situations in which learning in isolation-reared rats is enhanced or unimpaired compared to socially reared rats. The present experiments investigated the effects of isolation rearing on place navigation in the Morris water maze. Two(More)
Isolation rearing in the early stages of life has been shown to modify a variety of behaviours in many animals and the responsitivity to psychotropic drugs. The aims of the present study were to investigate the effects of isolation rearing on anxiety using the social interaction paradigm and to compare the effects of diazepam on social interaction(More)
It is widely accepted that early environmental influences may affect the behaviour of the adult animal and the responsivity to psychotropic drugs. Isolation rearing is an important variable in this regard. The present experiments compared the effects of isolation and social rearing of rats on the reinforcing properties of morphine. Male Lister hooded rats(More)
Social isolation has been demonstrated to alter individual reactivity to addictive drugs. The present experiments compared the effects of isolation rearing and socially rearing rats on the reinforcing properties of amphetamine. Male Lister hooded rats were housed from 21 days (weaning) either alone (isolation reared rats) or in groups of four rats per cage(More)
The present study determined whether rearing in social isolation alters the behavioural response produced by the selective noradrenaline uptake inhibitor, desipramine when rats are exposed to the forced swimming test or an open field arena. Male Wistar rats were raised from weaning either alone (isolation rearing) or in groups of five or six rats/cage(More)
Free recall of words has been extensively used in psychopharmacology to assess the effects of CNS-active drugs on memory functions. However, there is a relative lack of information on the impact of word frequency on the subsequent recall of words following the administration of psychoactive drugs. The present double-blind, placebo-controlled,(More)
Psychological stress during the early stage of life has b~en shown to alter the behaviors and the neurochemical properties of the adult animals and modify the responsitivity to various psychoactive agents (1-3). Objective: The aim of the present experiment was to determined whether stress during brain development (social isolation from weaning) alters the(More)
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