Noor Mustafa

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2DG causes cytotoxicity in cancer cells by disrupting thiol metabolism while Doxorubicin (DOX) induces cytotoxicity in tumor cells by generating reactive oxygen species (ROS). Here we examined the combined cytotoxic action of 2DG and DOX in rapidly dividing T47D breast cancer cells vs. slowly growing MCF-7 breast cancer cells. T47D cells exposed to the(More)
BACKGROUND The study was conducted to measure the extent of androgenic steroids abuse among two targeted groups in Jordan, college students and athletes, and the risk factors associated with this abuse. METHODS Five hundred and three Jordanian collegiate students and 154 bodybuilding athletes completed a three section questionnaire that investigated(More)
صخلملا This study was designed to evaluate the cytotoxic effect ةتبن قارولأ يئاملا صلختسملا ةيمس ىدم ميقتل ةساردلا هذه تممص ايلاخ ضر MDA-MB231 و FaDu ةدملل ةيناطرسلا ايلاخلا ةجلا يف تابارطضاب صلختسملا اذهب لختسم ص ملا ةتبن قارولأ يئا © 2009 Jordan Journal of Biological Sciences. All rights reserved
SMARCA4 chromatin remodelling factor is mutated in 11% of Coffin-Siris syndrome (CSS) patients and in almost all small-cell carcinoma of the ovary hypercalcaemic type (SCCOHT) tumours. Missense mutations with gain-of-function or dominant-negative effects are associated with CSS, whereas inactivating mutations, leading to loss of SMARCA4 expression, have(More)
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