Noemi Lala

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Migraine is a common type of headache and its most severe attacks are usually treated with triptans, the efficacy of which is extremely variable. Several SNPs in genes involved in metabolism and target mechanisms of triptans have been described. To define an association between genetic profile and triptan response, we classified a migrainous population on(More)
IMPORTANCE OF THE FIELD Migraine is a debilitating and painful neurological disorder affecting millions of people worldwide and often worsened by chronification. Triptans represent a powerful pharmacological resource in migraine management; nevertheless, a significant portion of treated patients do not obtain consistent pain relief through triptans.(More)
INTRODUCTION Migraine is the most common painful neurological disorder, affecting 13% of the general population. Triptans represent a powerful pharmacological tool in acute migraine treatment, however, a significant portion of treated patients cannot have access to this class due to possible adverse affects. Today, a total of seven triptan molecules are(More)
BACKGROUND Risk factors for suicide are at least partially heritable and functional polymorphisms of targeted genes have been suggested to be implicated in the pathogenesis of this phenomenon. However, other studies examining the association between specific gene variants and suicide revealed inconsistent findings. We aims to evaluate the possible(More)
The aim of this review is to assess the current evidence in scientific literature that supports the use of physical activity as a fundamental tool for primary and secondary prevention and to encourage its use conscientiously. Observational studies and international guidelines have been examined to evaluate the positive effects of physical activity as(More)
OBJECTIVES The aim of this cross-sectional study was to assess whether stagnation dimensions and depression were associated with perceived disability in chronic migraineurs. METHODS Participants were 69 consecutive adult outpatients admitted to the Regional Referral Headache Centre of the Sant'Andrea Hospital in Rome, Italy. Patients were administered the(More)
AIM Guidelines established preoperative cardiac management of the patient undergoing non-cardiac surgery in hospitalization. Regarding the patients undergoing the surgery in DS, the management is not defined. Aim of this study was to evaluate the appropriateness of the cardiological consultation requested by the patients undergoing surgery with this method.(More)
The Master in Headache Medicine has accomplished its 12 th cycle of life [1]. At the time of its activation we acknowledged the necessity of an academic education thought to support the growth of a subspecialty included in major disciplines like neurology, internal medicine, emergency medicine, pharmacology and pain medicine. The challenge then was to(More)
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