Noella Gardella

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Resistance to extended-spectrum cephalosporins is often associated with plasmid encoded extended spectrum beta-lactamases (ESBL). In order to evaluate the prevalence and diversity of ESBLs in enterobacteria in our city, a 1-month-period survey was carried out from April to May 2000. Extended-spectrum-cephalosporin-resistant strains, isolated from inpatient(More)
Sixty-nine community-associated methicillin-resistant Staphylococcus aureus recovered in 6 healthcare centers from northeastern and eastern Argentina were genotyped by pulsed-field gel electrophoresis. The predominant pulsotype was widely distributed harbored SCCmec type IV and Panton-Valentine leukocidin genes. Representative isolates were characterized by(More)
BACKGROUND Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is now the most common cause of skin and skin structure infections (SSSI) in several world regions. In Argentina prospective, multicenter clinical studies have only been conducted in pediatric populations. OBJECTIVE PRIMARY: describe the prevalence, clinical and(More)
Community-acquired methicillin-resistant Staphylococcus aureus infections in a hospital for acute diseases. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent pathogens associated with nosocomial infections. However, most recently, MRSA has arisen as an emerging community pathogen, causing serious infections, mainly among young(More)
Staphylococcus aureus protein A (SpA) plays a critical role in the induction of inflammation. This study was aimed to determine whether the number of short sequence repeats (SSRs) present in the polymorphic region modulates the inflammatory response induced by SpA. We demonstrated that there is a dose-response effect in the activation of interferon (IFN)-β(More)
Historically, infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have been associated with healthcare settings. However, since the 1990s, community-acquired MRSA (CA-MRSA) infections have been increasingly recognized [1]. The microorganisms involved differ from those related to nosocomial infections in the presence of type IV(More)
The aim of this study was to characterize methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered from different infectious sites of hospitalized patients at two university hospitals. Fourteen isolates were analyzed by repetitive sequence based PCR (Rep-PCR), randomly amplified polymorphic DNA assay (RAPD-PCR), and pulsed-field gel(More)
We analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced alpha-toxin; 96% and 100% of them displayed positive results(More)
Strain typing is an integral part of epidemiological investigations of bacterial infections. Typing methods fall into two broad categories: phenotypic and genotypic methods. Phenotypic methods are those that characterize the products of gene expression in order to differentiate strains. Properties such as biochemical profiles, antimicrobial susceptibility(More)