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This paper presents a new algorithm for scheduling of sporadic task systems with arbitrary deadlines on identical multiprocessor platforms. The algorithm is based on the concept of semi-partitioned scheduling, in which most tasks are fixed to specific processors, while a few tasks migrate across processors. Particularly, we design the algorithm so that(More)
  • Joseph R Arron, Monte M Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao +9 others
  • 2006
Trisomy 21 results in Down's syndrome, but little is known about how a 1.5-fold increase in gene dosage produces the pleiotropic phenotypes of Down's syndrome. Here we report that two genes, DSCR1 and DYRK1A , lie within the critical region of human chromosome 21 and act synergistically to prevent nuclear occupancy of NFATc transcription factors, which are(More)
Serotonergic antidepressant drugs have been commonly used to treat mood and anxiety disorders, and increasing evidence suggests potential use of these drugs beyond current antidepressant therapeutics. Facilitation of adult neurogenesis in the hippocampal dentate gyrus has been suggested to be a candidate mechanism of action of antidepressant drugs, but this(More)
α-Synuclein (α-syn), the main component of Lewy bodies, was identified as a genetic risk factor for idiopathic Parkinson's disease (PD). As a model for PD, we generated human α-syn bacterial artificial chromosome transgenic mice (BAC tg mice) harboring the entire human α-syn gene and its gene expression regulatory regions. The α-syn BAC tg mice manifested(More)
This paper presents a new algorithm for fixed-priority scheduling of sporadic task systems on multiprocessors. The algorithm is categorized to such a scheduling class that qualifies a few tasks to migrate across processors, while most tasks are fixed to particular processors. We design the algorithm so that a task is qualified to migrate, only if it cannot(More)
Elucidating the neural and genetic factors underlying psychiatric illness is hampered by current methods of clinical diagnosis. The identification and investigation of clinical endophenotypes may be one solution, but represents a considerable challenge in human subjects. Here we report that mice heterozygous for a null mutation of the alpha-isoform of(More)
Extended T-N Plane Abstraction (E-TNPA) proposed in this paper realizes work-conserving and efficient optimal real-time scheduling on multiprocessors relative to the original T-N Plane Abstraction (TNPA). Additionally a scheduling algorithm named NVNLF (No Virtual Nodal Laxity First) is presented for E-TNPA. E-TNPA and NVNLF relax the restrictions of TNPA(More)