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We propose a novel <i>cross-sectional structural analysis</i> technique that efficiently detects critical stress inside a 3D object. We slice the object into cross-sections and compute stress based on bending momentum equilibrium. Unlike traditional approaches based on finite element methods, our method does not require a volumetric mesh or solution of(More)
It is common to use computers to design shapes of physical objects such as furniture, but geometric modeling and the physical validity of shapes are conventionally considered independently. This makes creating aesthetically pleasing yet physically valid models challenging. In this paper, we propose an interactive design framework for the efficient and(More)
OBJECTIVE The objective of this study was to examine the influence of the morphologic characteristics of the bicuspid aortic valve on its disease progression by comparing the motion, stress/strain distribution, and blood flow of normal and stenotic tricuspid valves using simulation models. METHODS Bicuspid, stenotic tricuspid with commissural fusion or(More)
We present a novel interactive tool for garment design that enables, for the first time, interactive bidirectional editing between 2D patterns and 3D high-fidelity simulated draped forms. This provides a continuous, interactive, and natural design modality in which 2D and 3D representations are simultaneously visible and seamlessly maintain correspondence.(More)
OBJECTIVE Recently, various modifications have been made to aortic root replacement procedures to include the pseudosinus in the synthetic graft, but its effect on valve function still remains to be elucidated. The purpose of this study was to compare the flow dynamics and its influence on the stress/strain in the valve leaflet in two types of aortic root,(More)
This paper introduces novel interactive techniques for designing original hand-launched free-flight glider airplanes which can actually fly. The aerodynamic properties of a glider aircraft depend on their shape, imposing significant design constraints. We present a compact and efficient representation of glider aerodynamics that can be fit to real-world(More)
Lovastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, inhibits the synthesis of mevalonic acid and is widely used as an anti-atherosclerotic drug. The macrophage scavenger receptor (SCR), a trimeric membrane glycoprotein, is postulated to play a key role in atheroma macrophage foam cell formation. HMG-CoA reductase is(More)
We present an example-based elastic deformation method that runs in real time. Example-based elastic deformation was originally presented by Martin et al. [MTGG11], where an artist can intuitively control elastic material behaviors by simply giving example poses. Their FEM-based approach is, however, computationally expensive requiring nonlinear(More)
To clarify the role of PDGF A-chain in hypertensive vascular hypertrophy of spontaneously hypertensive rats (SHRs), we studied levels of PDGF A-chain gene expression and transcription factors related to the gene in vascular smooth muscle cells (VSMCs) of SHRs in vivo. RNase protection assay and in situ hybridization showed that PDGF A-chain mRNA levels in(More)
We present a novel method to simulate complex bending and twisting of elastic rods. Elastic rods are commonly simulated using force based methods, such as the finite element method. These methods are accurate, but do not directly fit into the more efficient position-based dynamics framework, since the definition of material frames are not entirely based on(More)