Nobutoshi Nakagawa

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Acute depletion of brain tryptophan (TRP) levels in humans has been used as a biochemical model of depression. In this study, we examined the effects of consumption of a diet low in TRP on emotional behavior in mice. Specifically, we assessed various parameters of emotional behavior in mice fed a TRP-limited diet for at least 1 mo. TRP-limited mice showed(More)
The currents activated in single cells of an epithelial cell line from renal tubules of Xenopus laevis, were studied, using a whole-cell voltage-clamp technique. After the patched membrane was broken for the whole-cell recording, the currents developed transiently, reaching a peak in 20 min, in cells held under voltage-clamp. The currents did not show(More)
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