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- Publications
- Influence
Cosmetic benefits of astaxanthin on humans subjects.
- Kumi Tominaga, Nobuko Hongo, Mariko Karato, E. Yamashita
- Biology, Medicine
- Acta biochimica Polonica
- 17 March 2012
Two human clinical studies were performed. One was an open-label non-controlled study involving 30 healthy female subjects for 8 weeks. Significant improvements were observed by combining 6 mg per… Expand
The structure of brazzein, a sweet-tasting protein from the wild African plant Pentadiplandra brazzeana.
- K. Nagata, Nobuko Hongo, +6 authors M. Tanokura
- Chemistry, Medicine
- Acta crystallographica. Section D, Biological…
- 1 April 2013
Brazzein is the smallest sweet-tasting protein and was isolated from the wild African plant Pentadiplandra brazzeana. The brazzein molecule consists of 54 amino-acid residues and four disulfide… Expand
Protective effects of astaxanthin on skin deterioration
- Kumi Tominaga, Nobuko Hongo, Mayuko Fujishita, Yu Takahashi, Yuki Adachi
- Medicine, Biology
- Journal of clinical biochemistry and nutrition
- 20 June 2017
Astaxanthin is a carotenoid with potent antioxidant and anti-inflammatory activity. To evaluate the anti-inflammatory effect of astaxanthin on skin deterioration, we confirmed its role in… Expand
Daily Fatigue—reducing Effect of Astaxanthin―A Randomized, Placebo—controlled, Double—blind, Parallel—group Study―
- Nobuko Hongo
- Medicine
- 2017
Objective To evaluate the effects of astaxanthin on the sense of fatigue occurring in daily life and to investigate the relationship of the fatigue-reducing effect with the antioxidative potential.… Expand
- 2
Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer’s Disease-Related Pathological Progression in the Hippocampus of AppNL-G-F/NL-G-F Mice
- Nobuko Hongo, Y. Takamura, +5 authors H. Nishijo
- Chemistry, Medicine
- Frontiers in Pharmacology
- 11 March 2020
Growing evidence suggests that oxidative stress due to amyloid β (Aβ) accumulation is involved in Alzheimer’s disease (AD) through the formation of amyloid plaque, which leads to hyperphosphorylation… Expand
Cosmetic benefits of oral supplementation combined with topical treatment of astaxanthin on humans subjects
- Kumi Tominaga, Nobuko Hongo, Mariko Karato, E. Yamashita
- Medicine
- 2011
- 1
The Safety of AstaREAL, an Astaxanthin Product Derived from Haematococcus pluvialis
- J. Takahashi, Nobuko Hongo, +4 authors N. Suzuki
- Medicine
- 2015
The Safety of AstaREAL, an Astaxanthin Product Derived from Haematococcus pluvialis Jiro TAKAHASHI1, Nobuko HONGO1, Shiro OHKI1, Akitoshi KITAMURA1, Hiroki TSUKAHARA1, Hoko KYO2, Nobutaka SUZUKI2 1… Expand
Cosmetic benefits of astaxanthin oral supplementation on humans subjects
- Kumi Tominaga, Nobuko Hongo, Mariko Karato, E. Yamashita
- Medicine
- 2011
Brazzein and structurally similar proteins: structural/functional comparisons
- K. Nagata, Nobuko Hongo, +6 authors M. Tanokura
- Chemistry
- 5 August 2014
Brazzein, a 6.5-kDa protein consisting of 54 amino acids and four disulfide bonds, is the smallest sweet-tasting protein yet isolated from the wild African plant Pentadiplandra brazzeana. Brazzein… Expand
Crystal Structure of Brazzein
- K. Nagata, Nobuko Hongo, +6 authors M. Tanokura
- Materials Science
- 27 March 2013