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OBJECTIVE To study the after-effect of theta burst stimulation (TBS) over the left sensorimotor cortex on the size of somatosensory as well as motor evoked potentials evoked from both hemispheres in healthy human subjects. METHODS We used a continuous TBS paradigm for 40 s (600 pulses) in which a burst of 3 transcranial magnetic stimuli at 50 Hz is(More)
Writer's cramp, or focal hand dystonia, is characterized by involuntary coactivation of antagonist or unnecessary muscles while writing or performing other tasks. Although the mechanism underlying this muscle overactivation is unknown, recent studies of changes in cerebral blood flow during writing have demonstrated a reduction in the activation of the(More)
In this paper, we review the state-of-the-art technologies for driver inattention monitoring, which can be classified into the following two main categories: 1) distraction and 2) fatigue. Driver inattention is a major factor in most traffic accidents. Research and development has actively been carried out for decades, with the goal of precisely determining(More)
Magnetic fields evoked by taste stimuli of the human tongue were measured over the whole head using a helmet-shaped 64 channel magnetoencephalography system in five normal subjects. The stimuli were 10% glucose and 0.3 M NaCl solutions and distilled water. The most prominent peak (N175m) appearing over the bilateral hemispheres had a latency of 150-210 ms.(More)
The behavioral, neurochemical and histological changes of rats subjected to 3 days treatment with intracerebroventricular infusion of beta-amyloid peptides(Abeta)(1-42) were investigated 20 days and 80 days after the surgery. Abeta(1-42) produced a dose-dependent and a time-dependent impairment in the spontaneous alternation performance in the Y-maze(More)
OBJECTIVE A general lack of longitudinal studies on interhemispheric interactions following stroke led us to use transcranial magnetic stimulation (TMS) to examine changes in corticospinal/intracortical excitability and transcallosal inhibition over a 1-year period following subcortical stroke. METHODS We measured TMS parameters such as motor threshold(More)
Early components of the somatosensory potential (SEP) evoked by tactile stimulation of the tongue were recorded from the scalp in 7 normal subjects and compared with those resulting from taps on the middle finger. (1) Unipolar but not bipolar recording of SEP to tapping the tongue failed to differentiate the early components from large EEG deflections of(More)
Repetitive stimulation of the bullfrog glossopharyngeal nerve at a rate of 100 Hz for 10 s and at a supra-maximal intensity resulted in little depression of the glossopharyngeal nerve responses to application of quinine and mechanical taps to the tongue, in a 30-40% decrease in the responses to salt, acid, water and warmed saline and in a 80% decrease in(More)
The relative position of the P50m and the N100m sources of the auditory evoked magnetic field remains unclear. Magnetoencephalography was performed in 24 normal subjects. Contralateral P50m to left and right ear stimulus was observed in 21 and 19hemispheres, respectively. Ipsilateral P50m to left and right ear stimulus was observed in 17 and 16hemispheres,(More)
OBJECTIVE To investigate the after-effects of theta burst TMS (TBS) on cortico-muscular synchronization, and on cortico-spinal excitability, in humans. METHODS We studied 10 healthy subjects using a continuous paradigm of TBS (cTBS), i.e. 600 pulses in 40s. Before and after the cTBS, coherence function was computed as a measure of cortico-muscular(More)