Noboru Ichihara

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BACKGROUND Radiofrequency applications around pulmonary vein (PV) ostia often induce vagal reflexes. OBJECTIVE This study aimed to evaluate the impact of the order of the targeted PV on the vagal response during second-generation cryoballoon ablation. METHODS Eighty-one consecutive paroxysmal atrial fibrillation (AF) patients undergoing cryoballoon(More)
BACKGROUND The latest guidelines define "long-term success" as freedom from atrial arrhythmia recurrence more than 36 months after procedures without any antiarrhythmic drug therapy. OBJECTIVE The purpose of this study was to investigate the clinical outcomes and procedural findings in patients with recurrence beyond "long-term success." METHODS Among(More)
BACKGROUND Periesophageal vagal nerve injury is recognized as a rare complication in atrial fibrillation ablation procedures. We investigated the factors associated with the occurrence of symptomatic periesophageal vagal nerve injury after pulmonary vein antrum isolation. METHODS AND RESULTS Overall, 535 consecutive patients who underwent sole pulmonary(More)
BACKGROUND Inflammation plays a prominent role in the etiology of the early recurrence of atrial fibrillation (ERAF). We prospectively compared the proportion of ERAF and time-course patterns of biomarkers between radiofrequency (RF) and cryoballoon (CB) ablation. METHODSANDRESULTS We enrolled 82 consecutive paroxysmal AF patients undergoing pulmonary(More)
BACKGROUND The superior vena cava (SVC) is an infrequent but important source of atrial fibrillation (AF), but is not always easy to identify. OBJECTIVE This study aimed to identify predictors of an arrhythmogenic SVC (a-SVC) in patients undergoing AF ablation. METHODS Eight hundred thirty-six consecutive patients undergoing AF ablation were analyzed.(More)
BACKGROUND Left phrenic nerve injury (PNI) can occur during cryoballoon ablation of the left pulmonary veins (PVs). This study aimed to evaluate the feasibility of monitoring the bilateral phrenic nerve function during cryoballoon ablation of atrial fibrillation (AF). METHODS Fifty consecutive paroxysmal AF patients undergoing cryoballoon ablation using(More)
BACKGROUND Phrenic nerve injury (PNI) is recognized as an important complication during atrial fibrillation ablation. This study aimed to investigate the incidence and outcome of PNI during superior vena cava isolation (SVCI) and circumferential pulmonary vein isolation (CPVI) using radiofrequency (RF) energy and the factors associated with its occurrence.(More)
BACKGROUND The utility of compound motor action potential (CMAP) monitoring for anticipating phrenic nerve injury (PNI) during cryoballoon ablation has been reported. We sought to compare two different CMAP recording techniques and evaluated the feasibility during pulmonary vein antrum isolation (PVAI) and superior vena cava isolation (SVCI) using(More)
BACKGROUND Right phrenic nerve injury (PNI) is a major concern during superior vena cava (SVC) isolation due to the anatomical close proximity. The functional and histological severity of PNI parallels the degree of the reduction in the compound motor action potential (CMAP) amplitude. This study aimed to evaluate the feasibility of monitoring CMAPs during(More)
BACKGROUND Clinical outcomes after atrial fibrillation (AF) ablation are evaluated using standard 24-h Holter monitoring, and the large spontaneous variability of AF episodes and incidence of silent AF are major limitations. Further, symptoms generally decrease after AF ablation. METHODS AND RESULTS: Newly developed extended external auto-trigger loop(More)