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- Publications
- Influence
Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic 11-demethyltomaymycin and its biologically inactive metabolite oxotomaymycin by Streptomyces achromogenes.
- L. Hurley, C. Gairola, N. V. Das
- Chemistry, Medicine
- Biochemistry
- 24 August 1976
11-Demethyltomaymycin, an antitumor antibiotic produced by Streptomyces achromogenes, and its biologically inactive metabolite oxotomaymycin are biosynthesized from L-tyrosine, DL-tryptophan, and… Expand
Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic sibiromycin by Streptosporangium sibiricum.
- L. Hurley, W. L. Lasswell, R. Malhotra, N. V. Das
- Chemistry, Medicine
- Biochemistry
- 18 September 1979
The biosynthesis of the antitumor antibiotic sibiromycin by Streptosporangium sibiricum requires the construction of four units: the amino sugar from glucose; the anthranilate ring from DL-tryptophan… Expand