Nitish Sharma

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A novel stability-indicating gradient reversed-phase ultra-performance liquid chromatographic (RP-UPLC) method was developed for the determination of purity of dorzolamide hydrochloride and timalol maleate in presence of their impurities, and forced degradation products and placebo. The method was developed using a Waters UPLC BEH C18, 100 × 2.1mm, 1.7 µm(More)
INTRODUCTION A selective, specific, and sensitive "Ultra High-Pressure Liquid Chromatography" (UPLC) method was developed for determination of candesartan cilexetil impurities as well asits degradent in tablet formulation. MATERIALS AND METHODS The chromatographic separation was performed on Waters Acquity UPLC system and BEH Shield RP18 column using(More)
The objective of current investigation was to study the degradation behaviour of eberconazole nitrate and mometasone furoate under different International Conference on harmonisation recommended stress condition using reverse phase high performance liquid chromatographic method and to establish validated stability-indicating high performance liquid(More)
A selective, specific and stability-indicating gradient reverse phase high-performance liquid chromatographic (HPLC) method was developed for the determination of Ranitidine in presence of its impurities, forced degradation products and placebo substances such as saccharide and parabens. Ultraviolet detection was performed at 230 nm. Separate portions of(More)
A selective, specific, and sensitive ultra-performance LC (UPLC) method was developed for determination of eszopiclone and its degradation products. The chromatographic separation was performed with a Waters ACQUITY UPLC system and BEH C18 column using gradient elution with mobile phases A and B. Mobile phase A was 0.01 M phosphate buffer with 0.2% (w/v)(More)
INTRODUCTION A novel and simple isocratic reverse phase liquid chromatographic (RP-LC) method was developed for the quantitative determination of antioxidant-butylated hydroxy toluene (BHT) in paricalcitol hard gelatin capsule. In the paricalcitol capsule BHT concentration is very low. This method is precisely able to estimate BHT at low concentration at(More)
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