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PURPOSE To assess the incidence of vitreomacular adhesion and traction in age-related macular degeneration (AMD), and to evaluate surgical treatment in a subset of patients with choroidal neovascularization (CNV) nonresponsive to anti-neovascular growth factor (anti-VEGF) treatment. DESIGN Retrospective observational case-control and interventional case(More)
PURPOSE Drusen are the hallmark of age-related macular degeneration (AMD), and substantial evidence exists that the amount of drusen and their effect on retinal pigment epithelium is a strong predictor of progression of AMD and vision loss. Until recently, it was not possible to quantitate the volume of the drusen. However, the use of image-stabilized(More)
PURPOSE To study the appearance of margins of geographic atrophy in high-resolution optical coherence tomography (OCT) images and to correlate those changes with fundus autofluorescence (FAF) imaging. DESIGN Retrospective, observational case study. METHODS Patients with geographic atrophy secondary to dry age-related macular degeneration were assessed(More)
PURPOSE To evaluate the response to primary bevacizumab treatment of eyes with age-related macular degeneration (AMD) and choroidal neovascularization (CNV) with a large pigment epithelial detachment (PED) component and to compare the increase in visual acuity and reabsorption of retinal fluid in PED eyes with eyes with CNV in AMD with a minimal to no PED(More)
PURPOSE To evaluate images taken with OTI-OPKO Spectral domain optical coherence tomography (OCT; OTI-OPKO Health Inc, Miami, FL)/scanning laser ophthalmoscope (resolution of 5-8 microm) and compare them with conventional StratusOCT (Carl Zeiss Meditec Inc, Dublin, CA) in eyes with epiretinal membranes (ERMs), macular edema, and vitreoretinal interface(More)
PURPOSE To describe the ocular manifestations of interferon induced sarcoidosis. METHODS Observational case report. RESULTS A 42-year-old woman with hepatitis C developed papillitis and macular edema together with cutaneous lesions 3 months after starting interferon and ribavirin therapy. The therapy was stopped. After 17 months of observation, visual(More)
AIM To determine whether colour or grey-scale images from high-resolution spectral optical coherence tomography (OCT) are superior in visualising clinically important details of retinal structures. METHODS Patients with macular pathologies were imaged using spectral OCT (OTI, Toronto, Canada). Two reviewers independently analysed the retinal structures(More)
It is shown that, given the ability to restructure wafer-level designs, there are different ways to employ redundancy. Redundancy is evaluated by estimating system computational availability over a mission lifetime. This technique is illustrated using two wafer-scale integration (WSI) case studies. The first is a very-fine-grained programmable systolic data(More)