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The increasing interest in time series data mining in the last decade has resulted in the introduction of a variety of similarity measures, representations, and algorithms. Surprisingly, this massive research effort has had little impact on real world applications. Real world practitioners who work with time series on a daily basis rarely take advantage of(More)
Biological species may remain distinct because of genetic isolation or ecological adaptation, but these two aspects do not always coincide. To establish the nature of the species boundary within a local bacterial population, we characterized a sympatric population of the bacterium Rhizobium leguminosarum by genomic sequencing of 72 isolates. Although all(More)
Recent advancements in sensor technology have made it possible to collect enormous amounts of data in real time. However, because of the sheer volume of data most of it will never be inspected by an algorithm, much less a human being. One way to mitigate this problem is to perform some type of anomaly (novelty /interestingness/surprisingness) detection and(More)
Our intestinal microbiota harbours a diverse bacterial community required for our health, sustenance and wellbeing. Intestinal colonization begins at birth and climaxes with the acquisition of two dominant groups of strict anaerobic bacteria belonging to the Firmicutes and Bacteroidetes phyla. Culture-independent, genomic approaches have transformed our(More)
BACKGROUND There are conflicting data on the risk of post-ERCP pancreatitis (PEP) related to self-expandable metallic stents (SEMSs). OBJECTIVE To compare rates of PEP in patients who undergo biliary drainage with SEMSs or polyethylene stents (PSs). DESIGN Retrospective, cohort study. SETTING Tertiary-care medical center. PATIENTS This study(More)
PURPOSE OF REVIEW Gastroenterologists will likely play a critical role in the treatment of obesity and its comorbidities, as novel endoluminal approaches demonstrate their safety and efficacy over the coming years. Understanding the relative advantages and shortcomings of the endoscopic tools and procedures currently under investigation will provide the(More)
We investigated the genomic diversity of a local population of the symbiotic bacterium Sinorhizobium medicae, isolated from the roots of wild Medicago lupulina plants, in order to assess genomic diversity, to identify genomic regions influenced by duplication, deletion or strong selection, and to explore the composition of the pan-genome. Partial genome(More)
PURPOSE OF STUDY With the availability of multiple positron emission tomography (PET) tracers for neurooncology, there is a need to define the appropriate tracer in a given clinical setting, and it is in this regard that we undertook this study to directly compare F-18 flurodeoxyglucose (FDG) PET and C-11 methionine (MET) PET for the evaluation of(More)
As more patients undergo bariatric surgery, gastroenterologists will increasingly encounter variant postsurgical anatomies and postoperative complications. We discuss the diagnosis and management of bleeding, ulcers, foreign bodies, stenoses, leaks, fistulas, pancreaticobiliary diseases, weight regain, and dilated outlets.
Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during a single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation of genomic changes with a “one-off” catastrophic event. However, the term has been used with varying operational(More)