Nitin Karnik

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BACKGROUND Coronary heart disease (CHD) is a major killer worldwide. Atherosclerosis, which is the basis of CHD, is believed to be an inflammatory disorder. Though various aspects of atherosclerosis are extensively studied, leukocytic hydrolytic enzymes are not studied very well with respect to CHD. AIM This study was planned to assess changes associated(More)
Free radicals play an important role in the pathogenesis of tissue damage in many clinical disorders, including atherosclerosis. Antioxidants protect the body from damage caused by free radicals. In this study we investigated oxidative stress, antioxidants and inflammatory molecules in patients with acute myocardial infarction. This study has been carried(More)
This case report describes a case of a 23 years old female who presented with clinical features of postpartum psychosis (Psychotic disorder not otherwise specified, DSM-IV). On investigation she was found to be suffering from Sheehan's syndrome (postpartum pituitary infarction). It was interesting to note that all the clinical features of Sheehan's syndrome(More)
BACKGROUND Ventilator associated pneumonia (VAP) is one of the commonest infection acquired in intensive care unit. VAP is associated with increased patients mortality and morbidity. Many cases of VAP may be prevented by simple preventive strategies. AIMS AND OBJECTIVES To note the incidence and outcome of patients with VAP. METHOD AND MATERIAL Total(More)
Fifty two patients of severe hypertension, diastolic blood pressure > or = 115 mmHg, with or without acute complications, were treated with sublingual nifedipine 10 mg or sublingual captopril 25 mg in a randomized prospective in patient study with careful clinical monitoring. Both the drugs were safe and effective in rapidly lowering blood pressure.(More)
In 102 cases of severe hypertension (DBP > or = 115 mm Hg), with or without acute complications, efficacy and safety of SL Nifedipine 10 mg (NIF), SL Captopril 25 mg (CAP), IV Metoprolol 15 mg (MET) and SL NIF + IV MET were studied in an inpatient trial. Maximum mean percent reduction in SBP was 13.3, 9.7, 15.7 and 19.9 and in DBP was 21.2, 13.9, 12.5 and(More)