Nitin I Kochar

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Curcumin is the lipid-soluble antioxidant compound obtained from the rhizome of Curcuma longa Linn, also known as turmeric. Curcumin targets multiple chemotherapeutic and inflammatory pathways and has demonstrated safety and tolerability in humans, supporting its potential as a therapeutic agent; however, the clinical literature lacks conclusive evidence(More)
Diabetic subjects exhibit low levels of nitric oxide (NO), its precursor L-arginine, and nitric oxide synthase (NOS) in tissues like endothelium and kidney. In view of this, we speculated that gastrointestinal (GI) dysfunction in diabetes could be related to similar changes in NO turnover in GI tissues. Hence, the studies were carried out in rats after(More)
Oxidative stress occurs in diabetic patients and experimental models of diabetes. The ability of L-arginine to ameliorate oxidative stress after treatment with alloxan was investigated in rats. Adult male rats were injected intraperitoneally with multiple doses of alloxan to produce experimental oxidative stress characteristic of diabetes mellitus. The rats(More)
Pharmacognostic standardization of the Varuna Kwatha Churna an ayurvedic formulation formulated from various medicinal plants as bark of varuna, pashanbheda rhizome, fruit of gokshura and rhizome of sunthi which is used to treat urolithiasis. The varuna kwatha churna manufactured by the formula in the ratio as specified in the ayurvedic formulary of India(More)
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