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The objective of this investigation was the assessment of the response rate of oral atenolol in patients with vasovagal syncope after 1 month of treatment. We randomized into two groups all patients referred to our unit who had had at least one episode of syncope or two episodes of presyncope 1 month before presentation and had a positive isuprel Tilt Table(More)
BACKGROUND Homocysteine is an intermediate compound formed during metabolism of methionine. The plasma level of homocysteine is dependent on the genetically regulated level of essential enzymes and the intake of folic acid, vitamin B6 (pyridoxine), and vitamin B12 (cobalamine). Elevated serum homocysteine levels are a known risk factor for coronary artery(More)
There is evidence that there is a bidirectional relationship between major depression and cardiovascular disorder (CVD): depressed patients are a population at risk for increased cardiac morbidity and mortality, and depression is more frequent in patients who suffer from CVD. There is also evidence that inflammatory and oxidative and nitrosative stress(More)
BACKGROUND Coronary magnetic resonance angiography is a noninvasive method to visualize coronary arteries. The objective of this study was to determine the accuracy of coronary magnetic resonance imaging in the detection of coronary artery stenosis. METHOD The authors studied 61 patients who were scheduled for their first diagnostic X-ray coronary(More)
The role of Chlamydia pneumoniae infection in precipitating acute coronary syndrome (ACS) is unclear. Some studies have indicated that intervention with macrolide antibiotics might reduce coronary events in patients with ACS. A double blind, randomized, placebo-control trial was conducted on 84 ACS patients. Patients were randomized to 30 days of treatment(More)
Percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) are both used widely for angina but information about their comparative efficacy is limited. This study compared the outcome of 358 consecutive patients undergoing initial revascularization for significant narrowing of the left anterior descending artery (LAD)(More)
Prior to exercise treadmill testing (ETT), 157 patients (92 males and 65 females) were interviewed twice separately, using a Thai version of the Rose questionnaire for angina pectoris. One interview was conducted by a physician and the other by a nurse. The questionnaire responses were compared with ETT results. Based on physician-conducted interview, the(More)
Chlamydia pneumoniae (C. pneumoniae) is an emerging infectious agent, with a spectrum of clinical manifestations, and it has recently been tentatively linked to atherosclerosis. In order to describe the seroprevalence of C. pneumoniae in Thailand, we evaluated 1,798 normal healthy subjects (aged 20-93 years) for anti-C. pneumoniae IgG and IgA. Specific(More)
  • N Mahanonda
  • 1998
Efforts to improve Percutaneous Transluminal Coronary Angioplasty (PTCA) have resulted in the usage of new antiplatelets, and antithrombotic agents. These new agents may increase bleeding complications. However, EPIC, EPILOG and CAPTURE trials showed benefits of 7E3, a GPIIb/IIIa platelets receptor blocker, in high risk PTCA patients. On the other hand,(More)
BACKGROUND Heart failure (HF) is primarily a disease of the elderly. The incidence of congestive heart failure (CHF) in Thailand has been increasing during the last 10 years. Unlike other diseases, physicians have only rough patients' symptoms and physical findings to guide the adequacy of treatment. Recently, there has been evidence of the role of brain(More)