Nishith Singh

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AIM Oxidative stress and ischaemia are suggested as possible mechanisms of contrast-induced nephropathy (CIN). Statins may offer renoprotection in both acute and chronic kidney diseases because of their antioxidant and anti-inflammatory properties. We investigated whether use of statins before non-emergent percutaneous coronary intervention (PCI) reduces(More)
Citrinin is the one of the well-known mycotoxins, which is possibly spread all over the world. The graded doses of citrinin (1, 3 and 5 ppm CIT in feed) in female Wistar rats 10 weeks prior to mating, during mating and during organogenesis resulted in resorptions and post implantation losses, decreased fetal body weights and crown-rump lengths in fetuses of(More)
Bone remodeling is the continuous process by which old bone is removed by bone-resorbing cells, the osteoclasts and replaced by new bone synthesized by bone forming cells, the osteoblasts. Osteoporosis is characterized by a progressive loss of bone mass and microarchitecture, which leads to increased fracture risk. Denosumab, a human monoclonal antibody(More)
OBJECTIVE To study the effects of losartan and atenolol on glucometabolic parameters in nondiabetic hypertensive patients. MATERIALS AND METHODS In a prospective, open-label, parallel group study, nondiabetic patients with mild to moderate hypertension were randomized to either losartan (titrated from 50 to 100 mg/day, n = 20) or atenolol (titrated from(More)
advice of psychiatrist. Systemic examination revealed no further abnormality. Her metabolic parameters and CT head was within normal limits. On day 2, patient was in sedated state, but there was no seizure episode or violent behavior. On day three, she was fully alert and well oriented. Since she was a young healthy female without any obvious cause for(More)
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