Nisha C Hazra

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OBJECTIVES To use primary care electronic health records (EHRs) to evaluate the health of men and women at age 100. DESIGN Population-based cohort study. SETTING Primary care database in the United Kingdom, 1990-2013. PARTICIPANTS Individuals reaching the age of 100 between 1990 and 2013 (N = 11,084, n = 8,982 women, n = 2,102 men). MEASUREMENTS(More)
OBJECTIVE Relapsing polychondritis is a rare disease characterized by cartilage inflammation. Our aim was to estimate the incidence, prevalence and mortality of relapsing polychondritis and describe the clinical features of relapsing polychondritis in a large population. METHODS All participants diagnosed with relapsing polychondritis were sampled from(More)
The role of hypertension management among octogenarians is controversial. In this long-term follow-up (>10 years) study, we estimated trends in hypertension prevalence, awareness, treatment, and control among octogenarians, and evaluated the relationship of systolic blood pressure (SBP) ranges with mortality. Data were based on the English Longitudinal(More)
OBJECTIVES To use primary care electronic health records (EHRs) to evaluate prescriptions and inappropriate prescribing in men and women at age 100. DESIGN Population-based cohort study. SETTING Primary care database in the United Kingdom, 1990 to 2013. PARTICIPANTS Individuals reaching the age of 100 between 1990 and 2013 (N = 11,084; n = 8,982(More)
BACKGROUND Management of high blood pressure (BP) in people over 80 years is controversial, but there is limited information available concerning the uptake of hypertension treatment at this age. OBJECTIVE To evaluate use of antihypertensive drugs and changes in SBP and DBP from 2001 to 2014 in men and women aged 80 years and over. METHODS Cohort study(More)
BACKGROUND Clinical trials show benefit from lowering systolic blood pressure (SBP) in people ≥80 years of age, but nonrandomized epidemiological studies suggest lower SBP may be associated with higher mortality. This study aimed to evaluate associations of SBP with all-cause mortality by frailty category >80 years of age and to evaluate SBP trajectories(More)
BACKGROUND Pancreatitis is an important condition with significant mortality. Primary care may have an important role to play in its prevention, early diagnosis, and ongoing management. AIM To evaluate incidence, case fatality, and clinical features of acute and chronic pancreatitis in a large population. DESIGN AND SETTING Population-based cohort study(More)
BACKGROUND In the "fourth stage" of epidemiological transition, the distribution of non-communicable diseases is expected to shift to more advanced ages, but age-specific changes beyond 80 years of age have not been reported. METHODS This study aimed to evaluate demographic and health transitions in a population aged 80 years and over in the United(More)
Ageing is assumed to be accompanied by greater health care expenditures but the association is also viewed as a ‘red herring’. This study aimed to evaluate whether age is associated with health care costs in the senior elderly, using electronic health records for 98,220 participants aged 80 years and over registered with the UK Clinical Practice Research(More)
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