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BACKGROUND & OBJECTIVES Ocular infection with Chlamydia trachomatis is a major public health problem in densely populated countries like India. The true prevalence of such infections is uncertain due to insufficient data available from India. The aim of this study was to do a retrospective analysis of C. trachomatis eye infections in patients attending the(More)
PURPOSE To assess the utility of polymerase chain reaction (PCR) in diagnosing fungal keratitis and compare its sensitivity and specificity with those of the conventional microbiologic techniques used in the authors' laboratory. METHODS A prospective nonrandomized investigation was undertaken at a tertiary-care ophthalmic facility to evaluate 40 eyes of(More)
All trademarks appearing in this paper are properties of their respective companies. Abstract There has been virtually no software localization into any of the major languages of India. One important reason for this is the fact that enabling Indic scripts at the base software level involves sophisticated computational process that are far from the(More)
BACKGROUND Herpes Simplex Virus (HSV) keratitis is a leading cause of corneal blindness. Definitive laboratory diagnosis is essential for timely management. Collection of corneal scrapings in patients with advanced epithelial keratitis and corneal thinning poses perforation risks; tear fluid is a feasible and convenient alternative but has not been widely(More)
This study was undertaken to determine in vivo permeability coefficients for fluoroquinolones and to assess its correlation with the permeability derived using reported models in the literature. Further, the aim was to develop novel QSPR model to predict corneal permeability for fluoroquinolones and test its suitability on other training sets. The in vivo(More)
Candida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nails of both hands. The sloughed out nail, on microscopy,(More)
Scrub typhus is a rickettsial disease, reported from many Asian countries including Nepal [1]. It is a zoonotic disease transmitted by the blood sucking larva (chigger) of the arthropod, mite. The causative agent of this disease, that is transmitted through the bite of the chigger is Orientia tsutsugamushi, an obligate intracellular organism. Though there(More)