Mechanism of the dealkylation of tertiary amines by hepatic oxygenases. Stable isotope studies with 1-benzyl-4-cyano-4-phenylpiperidine.
- R. Mcmahon, H. W. Culp, J. C. Craig, N. Ekwuribe
- Chemistry, Medicine
- Journal of medicinal chemistry
- 1 September 1979
The microsomal oxidative dealkylation of 1-benzyl-4-cyano-4-phenylpiperidine has been studied and the source of oxygen shown to be molecular oxygen. The rate of debenzylation was decreased by… Expand
Mitomycin antibiotics. Synthesis of 1-substituted 7-methoxymitosenes.