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The aim of this study was to test the hypotheses that 1) skeletal muscles of elderly subjects can adapt to a single endurance exercise bout and 2) endurance trained elderly subjects have higher expression/activity of oxidative and angiogenic proteins in skeletal muscle than untrained elderly people. To investigate this, lifelong endurance trained elderly(More)
Many lifestyle-related diseases are associated with low-grade inflammation and peroxisome proliferator activated receptor γ coactivator (PGC)-1α has been suggested to be protective against low-grade inflammation. However, whether these anti-inflammatory properties affect acute inflammation is not known. The aim of the present study was therefore to(More)
Subjects with a low birth weight (LBW) display increased risk of developing type 2 diabetes (T2D). We hypothesized that this is associated with defects in muscle adaptations following acute and regular physical activity, evident by impairments in the exercise-induced activation of AMPK signaling. We investigated 21 LBW and 21 normal birth weight (NBW)(More)
De Nine Hole Peg Board Test is o.a. door Mathiowetz(1) gestandaardiseerd en volgens ASHT(2) voldoende onderzocht op betrouwbaarheid en validiteit. Normaal waarden zijn bepaald waarbij onderscheid is gemaakt op leeftijd geslacht, dominantie. Adult norms for the nine hole peg test of finger dexterity. Upper extremity function in multiple sclerosis: improving(More)
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