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Mimotopes are peptides with affinities to given targets. They are readily obtained through biopanning against combinatorial peptide libraries constructed by phage display and other display technologies such as mRNA display, ribosome display, bacterial display and yeast display. Mimotopes have been used to infer the protein interaction sites and networks;(More)
A novel wavelet-based approach for medical image fusion is presented, which is developed by taking into not only account the characteristics of human visual system (HVS) but also the physical meaning of the wavelet coefficients. After the medical images to be fused are decomposed by the wavelet transform, different-fusion schemes for combining the(More)
The concealed information test (CIT) has drawn much attention and has been widely investigated in recent years. In this study, a novel CIT method based on denoised P3 and machine learning was proposed to improve the accuracy of lie detection. Thirty participants were chosen as the guilty and innocent participants to perform the paradigms of 3 types of(More)
The extraction of blood vessels from retinal images is an important and challenging task in medical analysis and diagnosis. This paper presents a novel hybrid automatic approach for the extraction of retinal image vessels. The method consists in the application of mathematical morphology and a fuzzy clustering algorithm followed by a purification procedure.(More)
The analysis and the characterization of atrial fibrillation (AF) requires, in a previous key step, the extraction of the atrial activity (AA) free from 12-lead electrocar-diogram (ECG). This contribution proposes a novel non-invasive approach for the AA estimation in AF episodes. The method is based on blind source extraction (BSE) using high order(More)
Predicting protein folding rate from amino acid sequence is an important challenge in computational and molecular biology. Over the past few years, many methods have been developed to reflect the correlation between the folding rates and protein structures and sequences. In this paper, we present an effective method, a combined neural network--genetic(More)
A new machine learning method referred to as F-score_ELM was proposed to classify the lying and truth-telling using the electroencephalogram (EEG) signals from 28 guilty and innocent subjects. Thirty-one features were extracted from the probe responses from these subjects. Then, a recently-developed classifier called extreme learning machine (ELM) was(More)