Ningning Jing

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In this paper, the knowledge gaps in the process of producing a new product are researched, and the mathematical models for the knowledge gaps are constructed. In the new product development process, the total knowledge gap is formed by the accumulation of the knowledge gaps produced from the stages of the development process. In a knowledge process cycle,(More)
The present study evaluated the ability of a Saccharomyces cerevisiae expression system to predict the pharmacokinetic (PK) activity of a calcium channel blocker in patients with distinct cytochrome P450 3A5 (CYP3A5) polymorphisms. The blood pressure lowering activity of amlodipine in 57 hypertensive patients with CYP3A5*1/*1, CYP3A5*1/*3, CYP3A5*4 and(More)
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