Ning-en Chang

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Angiosarcomas (AS) represent a heterogeneous group of malignant vascular tumors occurring not only in different anatomic locations but also in distinct clinical settings, such as radiation or associated chronic lymphedema. Although representing only 1% to 2% of soft tissue sarcomas, vascular sarcomas provide unique insight into the general process of tumor(More)
The diagnosis of myoepithelial (ME) tumors outside salivary glands remains challenging, especially in unusual clinical presentations, such as bone or visceral locations. A few reports have indicated EWSR1 gene rearrangement in soft tissue ME tumors, and, in one case each, the fusion partner was identified as either PBX1 or ZNF444. However, larger studies to(More)
Angiosarcoma (AS) is a distinct group of sarcomas characterized by upregulation of vascular-specific receptor tyrosine kinases, including TIE1, KDR, TEK, and FLT1. In keeping with the clinical heterogeneity, gene-expression profiling distinguishes two AS genomic clusters, which correlate with anatomical location and prior exposure to radiation. Furthermore,(More)
OBJECTIVE The aim of this study was to retrospectively compare surgical outcomes of the suprapubic arc sling (SPARC) and transobturator suburethral tape (MONARC) for treatment of stress urinary incontinence (SUI) in women. MATERIALS AND METHODS A total of 74 women treated for SUI using MONARC were compared with 32 treated using SPARC. Postoperative(More)
OBJECTIVE To investigate early postoperative complications of Burch colposuspension and the risk factors that may be associated with failure. METHODS We retrospectively reviewed the chart records of all patients who underwent Burch colposuspension from October 1997 to September 2002. Indications for colposuspension included urodynamic stress incontinence(More)
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