Ning Wen

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This study details the generation, verification, and implementation of a treatment planning system (TPS) couch top model for patient support system used in conjunction with a dedicated stereotactic linear accelerator. Couch top model was created within the TPS using CT simulation images of the kVue Calpyso-compatible couchtop (with rails). Verification(More)
This study was designed to evaluate contouring variability of human-and deformable-generated contours on planning CT (PCT) and CBCT for ten patients with low-or intermediate-risk prostate cancer. For each patient in this study, five radiation oncologists contoured the prostate, bladder, and rectum, on one PCT dataset and five CBCT datasets. Consensus(More)
Extravascular extracellular space (ve ) is a key parameter to characterize the tissue of cerebral tumors. This study introduces an artificial neural network (ANN) as a fast, direct, and accurate estimator of ve from a time trace of the longitudinal relaxation rate, ΔR1 (R1  = 1/T1 ), in DCE-MRI studies. Using the extended Tofts equation, a set of ΔR1(More)
Treatment of patients with multiple brain metastases using a single-isocenter volumetric modulated arc therapy (VMAT) has been shown to decrease treatment time with the tradeoff of larger low dose to the normal brain tissue. We have developed an efficient Projection Summing Optimization Algorithm to optimize the treatment geometry in order to reduce dose to(More)
BACKGROUND This study investigates the effect of gantry speed on 4DCBCT image quality and dose for the Varian On-Board Imager®. METHODS A thoracic 4DCBCT protocol was designed using a 125 kVp spectrum. Image quality parameters were evaluated for 4DCBCT acquisition using Catphan® phantom with real-time position management™ system for gantry speeds varying(More)
Operationally Critical Threat,Asset and Vulnerability Evaluation (OCTAVE) is introduced, together with its feasibility and deficiency when used in information security risk assessing for E-Government. AHP is imported to build a Risk Assessment Model of Information Security for E-Government based on OCTAVE, the value of information assets is defined(More)
To gate or not to gate-dosimetric evaluation comparing Gated vs. ITV-based methodologies in stereotactic ablative body radiotherapy (SABR) treatment of lung cancer Abstract Background: To compare retrospectively generated gated plans to conventional internal target volume (ITV)-based plans and to evaluate whether gated radiotherapy provides clinically(More)
PURPOSE This study was conducted to evaluate the advantages of jaw tracking for intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in spine radiosurgery. METHODS AND MATERIALS VMAT and IMRT plans were retrospectively generated for 10 RTOG 0631 spine radiosurgery protocol patients. A total of 8 plans for each patient(More)