Learn More
Human immunodeficiency virus-associated neurological disease (HAND) still causes significant morbidity, despite success reducing viral loads with combination antiretroviral therapy. The dopamine (DA) system is particularly vulnerable in HAND. We hypothesize that early, "reversible" DAergic synaptic dysfunction occurs long before DAergic neuron loss. As(More)
A central mechanism participates in sympathetic overdrive during insulin resistance (IR). Nitric oxide synthase (NOS) and nitric oxide (NO) modulate sympathetic nerve activity (SNA) in the paraventricular nucleus (PVN), which influences the autonomic regulation of cardiovascular responses. The aim of this study was to explore whether the NO system in the(More)
Batch experiments were performed to study the inactivation kinetics of Mycobacterium avium in the presence of monochloramine at 5-30 degrees C, pH 6-10, and 0.30-42.3 mg Cl2/ L. For each temperature and pH investigated, limiting high and low inactivation rates were observed for high and low disinfectant concentrations, respectively, within the range(More)
The phospholipid mediator platelet-activating factor (PAF), an endogenous modulator of glutamatergic neurotransmission, can also be secreted by brain mononuclear phagocytes during HIV-1 infection. Platelet-activating factor can induce neuronal apoptosis by NMDA receptor-dependent and independent mechanisms. We now demonstrate that acute administration of(More)
According to the feature of ad hoc networks, a predictive model of improved Elman recursive neural network is proposed. The predictive model can be used to predict the minimum hops of ad hoc nodes and thus can predict the movements of the nodes. A new algorithm to update and maintain the routing table is proposed based on the predictive model and routing(More)
Seth W. Perry,1,2 Justin Barbieri,1 Ning Tong,1,2 Oksana Polesskaya,4 Santosh Pudasaini,3 Angela Stout,1 Rebecca Lu,1 Michelle Kiebala,4 Sanjay B. Maggirwar,4 and Harris A. Gelbard1,2,4 1Center for Neural Development and Disease, 2Department of Neurology, Child Neurology Division, 3Graduate Program in Pathology, and 4Department of Microbiology and(More)
  • 1