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Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
Hepatocellular carcinoma is the third leading cause of deaths from cancer worldwide. Infection with the hepatitis B virus is one of the leading risk factors for developing hepatocellular carcinoma,Expand
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Neutrophil-specific chemokines are produced by astrocytic cells but not by neuronal cells.
BACKGROUND Neutrophils have a central role in the inflammatory conditions of the central nervous system (CNS). ELR chemokines direct neutrophil migration, but the source of chemokines in the CNS isExpand
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Identification and cross-species comparisons of CYP2F subfamily genes in mammals.
The cytochrome P450 2F (CYP2F) subfamily genes are currently known only from cDNA sequences in human, mouse, rat and goat. Compared to other divisions of the CYP2 gene family, the CYP2F subfamily isExpand
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Porcine reproductive and respiratory syndrome viruses predominant in southeastern China from 2004 to 2007 were from a common source and underwent further divergence
The full-length glycoprotein 5 (GP5) gene and a partial nonstructural protein 2 (NSP2) gene fragment of 46 porcine reproductive and respiratory syndrome viruses (PRRSV) from pig farms in southeasternExpand
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A novel SCN1A mutation identified in a Chinese family with familial hemiplegic migraine: A case report
Background Familial hemiplegic migraine (FHM) is a rare type of migraine with aura that is characterized by transient hemiparesis. Mutations in three genes (CACNA1A, ATP1A2, and SCN1A) have beenExpand
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Prognostic implications of aberrantly expressed methylation‑driven genes in hepatocellular carcinoma: A study based on The Cancer Genome Atlas.
RNA‑Sequencing and methylation data for hepatocellular carcinoma (HCC) were downloaded from The Cancer Genome Atlas (TCGA). The aberrantly expressed methylation‑driven genes in HCC and normal tissuesExpand
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Multifunctional Gadolinium-Doped Manganese Carbonate Nanoparticles for Targeted MR/Fluorescence Imaging of Tiny Brain Gliomas.
Manganese (Mn)-based nanoparticles have been proved to be promising MR T1 contrast agents for the diagnosis of brain tumors. However, most of them exhibit a low relaxation rate, resulting in anExpand
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Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade.
The atrophy of skeletal muscle is highly correlated with oxidative damage, excessive apoptosis and dysfunctional autophagy. Ampelopsin, a natural flavonoid, has multiple biological functionsExpand
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Subcellular Localization of a Plant Catalase-Phenol Oxidase, AcCATPO, from Amaranthus and Identification of a Non-canonical Peroxisome Targeting Signal
AcCATPO is a plant catalase-phenol oxidase recently identified from red amaranth. Its physiological function remains unexplored. As the starting step of functional analysis, here we report itsExpand
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Trillium tschonoskii maxim saponin mitigates D-galactose-induced brain aging of rats through rescuing dysfunctional autophagy mediated by Rheb-mTOR signal pathway.
During the expansion of aging population, the study correlated with brain aging is one of the important research topics. Developing novel and effective strategies for delaying brain aging is highlyExpand
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