Nils Strandberg Pedersen

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The isolation of Borrelia burgdorferi flagella and an enzyme-linked immunosorbent assay (ELISA) for detection of immunoglobulin G (IgG) and IgM to the B. burgdorferi flagellum are described. The diagnostic performance of the flagellum ELISA for serodiagnosis of Lyme disease was compared with the performance of a traditional whole cell B. burgdorferi sonic(More)
Male and female blood donors were grouped according to their blood donations, and the iron stores were estimated by a two-site immunoradiometric assay for ferritin. Hb serum iron, serum transferrin and transferrin saturation were also measured. A remarkable low serum ferritin concentration was found in male donors, who had donated blood one or two times.(More)
An enzyme-linked immunosorbent assay (ELISA) for detection of immunoglobulin G (IgG) and IgM to cardiolipin, lecithin, and cholesterol (VDRL [Venereal Disease Research Laboratory] ELISA) is described. The specificity of the VDRL ELISA for IgG and IgM was 99.6 and 99.5%, respectively, with sera from 1,008 persons without syphilis. For a group of patients(More)
Prion disease in man was first described as Creutzfeldt-Jacob disease (CJD) in the 1920s. CJD may have three different origins: sporadic, familial, due to mutations in the prion gene, or infectious, due to iatrogenic exposure to infectious brain material. As an example of the latter, kuru, in Papua New Guinea, was a variant of CJD transmitted by(More)
By crossed immunoelectrophoresis and Western blotting (immunoblotting), it was shown that Borrelia burgdorferi expresses the 60-kilodalton Common Antigen (CA) that is cross-reactive with an equivalent antigen in a wide range of remotely related bacteria. B. burgdorferi CA is strongly immunogenic. A B. burgdorferi genomic library was constructed by using a(More)
Case-control studies of cervical intra-epithelial neoplasia grade III (CIN III) and of invasive cervical cancer were carried out in Spain and Colombia to assess the relationship between cervical cancer and 6 common sexually transmitted agents (STAs). The CIN-III studies included 525 cases and 512 controls matched for age and for the place of recruitment;(More)
Iron status, including S-ferritin, S-iron, S-transferrin, transferrin saturation and haemoglobin, was assessed in 267 selected elderly subjects (128 male, 139 female) with a median age of 79 years (range 60-93 years) not suffering from diseases connected with inappropriately high S-ferritin. In both sexes, S-ferritin levels were practically constant over(More)
Iron status was assessed by measurement of serum ferritin (S-ferritin), transferrin saturation and haemoglobin (Hb) in 270 healthy Faroese children (153 ♂, 117 ♀) 4, 8 and 13 years old. There were no significant differences between the three variables in boys and girls. Geometric mean S-ferritin increased from 16 μg/l in 4-year-old children to 21 μg/l in(More)