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The purpose of this study was to determine the in vivo secretory activity of sweat glands from sedentary and trained subjects. Peripheral sweat production was determined using pilocarpine iontophoresis in 40 volunteers (10 sedentary men, 10 endurance-trained men, 10 sedentary women, 10 endurance-trained women). Peripheral sweat rate was significantly (P(More)
[18F]FEDAA1106 is a recently developed positron emission tomography (PET) radioligand for in vivo quantification of the 18 kDa translocator protein [TSPO or, as earlier called, the peripheral benzodiazepine receptor (PBR)]. TSPO imaging is expected to be useful for the clinical evaluation of neuroinflammatory diseases. The aim of this study was to provide(More)
BACKGROUND (S,S)-[F]FMeNER-D2 is a recently developed norepinephrine transporter ligand which is a potentially useful radiotracer for mapping the brain and heart norepinephrine transporter in vivo using positron emission tomography. In this work, we quantified the biodistribution over time and radiation exposure to multiple organs with (S,S)-[F]FMeNER-D2.(More)
Isokinetic leg strength and fatigue were measured in 24 male U.S. Marine Corps volunteers in a simulated sleep loss and unusually heavy work scenario. Knee extension and flexion peak torque (PT) were measured at three isokinetic speeds (1.57, 2.62 and 3.66 rad·s−1) followed by 45 consecutive maximal reciprocal contractions at 3.14 rad·s−1 to measure fatigue(More)
The purpose of this study was to determine the validity and reliability of a timed 5 km cycle ergometer ride to predict maximum oxygen uptake (VO2max). Fifty-two healthy volunteers had their VO2max determined during a maximal treadmill run. They also performed a timed 5 km cycle ergometer ride. The resistance setting for the cycle ride was set at a rate of(More)
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