Nils Lichtenberg

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Complement production by bronchoalveolar macrophages recovered from 8 normal volunteers and 15 patients with a variety of lung diseases was measured functionally and immunochemically. While macrophages from all eight normals demonstrated the capacity to secrete hemolytically active C2 and factor B within 48 hr of culture at consistent rates, bronchoalveolar(More)
The Hauser operation for patellar dislocation was performed in 34 women and 20 men, median age 18 (3-55) years; one leg was amputated because of wound infection with chronic septic arthritis. At the time of follow-up, 8 (3-32) years after the operation 57 knees had normal or almost normal patellar stability, but only 26 knees were free from pain. Only 16(More)
We report the inactivation of the third component of complement (C3) by hydroxylamine. C3 hemolytic and covalent binding activities decline with identical kinetics, demonstrating a direct correlation between the two activities. We conclude that covalent, surface-bound C3b is hemolytically active. The inactivation of C3 is first order with respect to(More)
The availability of techniques for establishment of primary, long term monolayers of breast milk macrophages and blood monocytes permitted a direct comparison of biosynthetic functions of human tissue macrophage and its progenitor. In addition to previously described morphological differences, four specific characteristics of the breast milk macrophage were(More)
We have shown that the labile binding site of C3b interacts covalently with receptive surfaces. We report here an analogous study of the interaction between the labile binding sites of the closely related complement proteins, C4 and C5, with sheep erythrocyte membranes. We find that i) C4b binds covalently to cell surface components; ii) the bond between(More)
We report the case of a 21-year ice hockey player with an accessory soleus muscle located medially in the ankle region. The swelling made it increasingly difficult for him to fit his skating boots and caused some pain during play. He was successfully treated by excising the muscle. Previously, the diagnosis was verified surgically in most reported cases.(More)
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