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  • Anirudh Muralidharan Gautam, Tausif Ahmed, +6 authors Jyoti Paliwal
  • Medicine
  • Journal of clinical pharmacology
  • 2011 (First Publication: 1 November 2011)
  • Arterolane (RBx 11160) maleate is a novel, rapidly acting synthetic trioxolane antimalarial compound being developed by Ranbaxy Research Laboratories (Haryana, India). It is presently under phase IIIContinue Reading
  • Ekta Varshney, Nilanjan Saha, Monika Tandon, Vikesh Shrivastava, Shakir Ali
  • Medicine
  • SpringerPlus
  • 2012 (First Publication: 16 October 2012)
  • Identification of poor and rapid metabolizers for the category of drugs metabolized by cytochrome P450 2B6 (CYP2B6) is important for understanding the differences in clinical responses of drugsContinue Reading
  • Neena Valecha, Srivicha Krudsood, +17 authors Nilanjan Saha
  • Medicine
  • Clinical infectious diseases : an official…
  • 2012 (First Publication: 1 September 2012)
  • BACKGROUND Artemisinin-based combination therapy is the first-line treatment for uncomplicated falciparum malaria. This study assessed the antimalarial efficacy and safety of a combination of 150 mgContinue Reading
  • Nilanjan Saha, Joerg J. Moehrle, Anita Zutshi, Pradeep kumar Sharma, Pawandeep Kaur, Sunil S. Iyer
  • Medicine
  • Journal of clinical pharmacology
  • 2014 (First Publication: 1 April 2014)
  • Arterolane (RBx11160, OZ277) maleate is a rapidly acting synthetic trioxolane anti-malarial. This randomized, placebo controlled study was a phase I study to evaluate the clinical safety andContinue Reading
  • Neena Valecha, Sornchai Looareesuwan, +15 authors Anders Björkman
  • Medicine
  • Clinical infectious diseases : an official…
  • 2010 (First Publication: 15 September 2010)
  • BACKGROUND Drug-resistant Plasmodium falciparum malaria necessitates development of novel drugs for treatment.The present study assessed the efficacy and safety of 3 dose levels of arterolane (RBxContinue Reading
  • Offianan Andre Toure, Neena Valecha, +30 authors Paul T. Swoboda
  • Medicine
  • Clinical infectious diseases : an official…
  • 2016 (First Publication: 15 April 2016)
  • BACKGROUND Artemisinins, which are derived from plants, are subject to risk of supply interruption due to climatic changes. Consequently, an effort to identify a new synthetic antimalarial wasContinue Reading
  • Offianan Andre Toure, Stephen Rulisa, +9 authors Neena Valecha
  • Medicine
  • Malaria Journal
  • 2015 (First Publication: 25 November 2015)
  • AbstractBackgroundThe World Health Organization (WHO) recommends artemisinin combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria. The present studyContinue Reading
  • Md Tarique Imam, Shobana Venkateshan, Monika Tandon, Nilanjan Saha, Krishna K. Pillai
  • Medicine
  • Journal of clinical pharmacology
  • 2011 (First Publication: 1 December 2011)
  • The authors compared US Food and Drug Administration (FDA) and 9 pharmacologically guided approaches (PGAs; simple allometry, maximum life span potential [MLP], brain weight, rule of exponent [ROE],Continue Reading