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CONTEXT Metabolic syndrome and periodontitis both have an increasing prevalence worldwide; however, limited information is available on their association. OBJECTIVE The objective of the study was to assess the association between periodontitis and the metabolic syndrome in a cross-sectional survey of a nationally representative sample of the(More)
Titanium (Ti) is the material of choice for dental and orthopaedic implants due to its highly biocompatible nature. Modification of the implant surface, either topographically (as roughness) or chemically, can promote accelerated osteogenesis in vivo and greatly increase bone-implant contact and bonding strength. In this paper, we sought to characterise the(More)
Overweight and obesity have been suggested to be associated with periodontitis as published in studies and narrative summaries. This project presents results of a systematic review investigating the association between overweight or obesity (as defined by the World Health Organization) and periodontitis. Search strategy included electronic and hand(More)
BACKGROUND There is a lack of consensus on measures to assess implant performance in clinical research. OBJECTIVES To investigate the outcomes measures and reference groups employed to evaluate and compare implant success and failure. DATA SOURCES MEDLINE (OVID) and Web of Science with searching reference lists of included papers. STUDY ELIGIBILITY(More)
UNLABELLED Periodontitis is a ubiquitous and irreversible inflammatory condition and represents a significant public health burden. Severe periodontitis affects over 11% of adults, is a major cause of tooth loss impacting negatively upon speech, nutrition, quality of life and self-esteem, and has systemic inflammatory consequences. Periodontitis is(More)
The aim of this study was to determine leukocyte telomere length (LTL) in individuals with periodontitis and controls, exploring its relationship with systemic inflammation and oxidative stress. Five hundred sixty-three participants were recruited for this case-control study: 356 subjects with and 207 subjects without periodontitis. LTL was measured by a(More)
AIM The primary aim of this study was to retrospectively ascertain disease progression in a cohort of aggressive periodontitis patients (AgP). MATERIALS AND METHODS Patients treated at a specialist setting and referred back to general practice for periodontal maintenance were recalled and examined in a single visit. Disease progression during follow-up(More)
BACKGROUND Interleukin-6 (IL-6) concentrations vary substantially among individuals. This study aimed to identify novel genetic markers to explain these differences. METHODS We sequenced a region 6-kb upstream of the IL6 [interleukin 6 (interferon, beta 2)] transcription start site in a search for functional variants and detected 3 common variants:(More)
BACKGROUND Viruses such as Human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) have been proposed to be periodontal pathogens. The aim of this study was to analyse the presence of herpesvirus DNA in subgingival plaque samples of patients with different forms of periodontitis and in healthy periodontia. MATERIALS AND METHODS A total of 140 ethnically(More)
BACKGROUND Several epidemiological studies have reported an association between metabolic syndrome (MetS) and periodontal diseases (PDs). The aim of this systematic review was to investigate the existence and magnitude of this association. MATERIALS AND METHODS A systematic search of the literature was conducted looking for case-control, cross-sectional,(More)