Nikolay N Kalitin

Learn More
We studied the expression of genes encoding vascular endothelial growth factors VEGF-A, VEGF-C, VEGF-D and their receptors in cell cultures of human multiple myeloma IM9, RPMI 1640, RPMI 8226. The studied cells did not differ by the expression of growth factors. Expression of VEGFR1 receptor was detected only in IM9 cells and VEGFR2 and VEGFR3 receptors(More)
In this study, for the first time the expression of β₂ and β₄ isoforms of RARβ gene was investigated in group of 19 patients with the newly diagnosed multiple myeloma. The expression of both RARβ₂ and RARβ₄ isoforms was detected in all patients, but it was different and had opposite tendency. We showed that RARβ₄ expression level positively correlated with(More)
The regulation of vascular endothelial growth factors C (VEGF-C) and D (VEGF-D), and their receptor VEGFR3 gene and protein expression by all-trans-retinoic acid (atRA) in A549 lung cancer cells, was investigated. We showed that atRA treatment increased VEGF-C, VEGF-D, and VEGFR3 protein and mRNA contents in dose-dependent manner. atRA-mediated increase of(More)
AIM To assess the significance of gene expression of the vascular endothelial growth factor-A (VEGF-A) and its interacting receptors VEGFR1 and VEGFR2 as potential diagnostic and prognostic molecular markers in patients with myelodysplastic syndrome (MDS). MATERIAL AND METHODS A real time polymerase chain reaction (RT-PCR) assay was used to investigate(More)
  • 1