Nikolaus Michalopoulos

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194 Background: One step nucleic acid (OSNA) is a recently developed molecular diagnostic assay to detect lymph node metastases. Aim of the present study was to assess OSNA for intra-operative detection of sentinel node metastases with use of standard histopathology as the "gold standard." Moreover, discordant cases were further investigated to assess their(More)
59 Background: The international randomised contolled TARGeted Intraoperative radioTherapy (TARGIT) trial has demonstrated non-inferiority between the novel technique of TARGIT (intra-operative radiotherapy with Intrabeam) and conventional whole-breast external beam radiotherapy (EBRT) in women with early breast cancer, in terms of the primary outcome(More)
22 Background: Sentinel lymph node biopsy (SLNB) is a standard practice for staging the axilla in breast cancer. Access to nuclear medicine department and sentinel node imaging remain an issue in number of hospitals in the UK and rest of the world. Preoperative scintigrams are performed to confirm uptake of radioactivity and localisation of nodes in centres(More)
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