Nikolaus Aebli

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STUDY DESIGN An experimental study of cardiovascular complications that arise during vertebroplasty was conducted. OBJECTIVE To investigate the sequential occurrence of fat embolism and hypotension during vertebroplasty. SUMMARY OF BACKGROUND DATA Vertebroplasty, the augmentation of vertebrae with polymethylmethacrylate, is a technique for treating(More)
BACKGROUND CONTEXT Neuropathic (Charcot) spinal arthropathy (CSA) is a rare but progressive and severe degenerative disease that develops in the absence of deep sensation, for example, after spinal cord injury. The diagnosis of CSA is often delayed as a result of the late onset or slow progression of the disease and the nonspecific nature of the reported(More)
Vertebral cement augmentation is reported to be a safe and effective technique for providing stabilization and pain relief. However, adjacent intervertebral discs may be at risk of accelerated degeneration as a result of aggravated nutritional constraints. Therefore, we investigated the effects of injecting polymethylmethacrylate (PMMA) into three adjacent(More)
Concerns have been raised that the use of calcium phosphate (CaP) cements for the augmentation of fractured, osteoporotic bones may aggravate cardiovascular deterioration in the event of pulmonary cement embolism by stimulating coagulation. The aim of the present study was therefore to investigate the cardiovascular changes after pulmonary embolism of CaP(More)
BACKGROUND AND PURPOSE There are very few data concerning the outcome after short-segment posterior stabilization and anterior spondylodesis with rib grafts in patients suffering from unstable thoracolumbar burst fractures. We have therefore investigated the clinical and radiographic outcome after posterior bisegmental instrumentation and monosegmental(More)
STUDY DESIGN An experimental study of cardiovascular complications arising during vertebroplasty (VP) of multiple levels in sheep. OBJECTIVES To investigate the effect of pressurizing vertebral bodies during VP using different materials in the development of fat embolism (FE) and any associated cardiovascular changes. SUMMARY OF BACKGROUND DATA(More)
STUDY DESIGN Experimental study of temperature profiles during vertebroplasty. OBJECTIVES To define accurate temperature profiles during vertebroplasty in an in vivo animal model. SUMMARY OF BACKGROUND DATA Controversy still exists whether vertebroplasty achieves its analgesic effect by stabilizing fracture fragments or due to thermal damage of sensory(More)
Research efforts aim at enhancing early osseointegration of cementless implants to improve early fixation and, thus, reduce the risk of loosening. The aim of the present study was to investigate whether bone morphogenetic protein (BMP) 2 had a positive effect on the osseointegration of hydroxyapatite-coated implants. Hydroxyapatite (HA) implants (perforated(More)
BACKGROUND Fat embolism (FE), the release of bone marrow contents into the circulation and the subsequent cardiovascular changes, is still a potentially fatal com-plication during orthopedic surgery. Different causative factors have been suggested, but the exact pathomechanism of FE still remains unclear. We investigated the role of polymethylmethacrylate(More)