Nikolaos Spyrou

Learn More
Lorcaserin is a serotonin 5-hydroxytryptamine 2c receptor agonist effective in treating obesity. Studies in rodents have shown that lorcaserin acts in the brain to exert its weight-reducing effects, but this has not yet been studied in humans. We performed a randomized, placebo-controlled, double-blind trial with 48 obese participants and used functional(More)
The passage of technetium-labelled methylene diphosphonate (99mTc-MDP) across rat bone was examined by autoradiography. The autoradiographs showed that shortly after an injection of the bone-seeking agent there was activity outside the bone, within the bone marrow and also adjacent to the highly vascular epiphysial plate; the distribution of the isotope in(More)
Abbreviations: CRP, C-reactive activated receptor-γ; DPP-4, dipe transcription factor 4; SIRT1, sirtu Uncoupling Protein 1; DHEA, Deh necrosis factor; NAFLD, non-alcoh PBMCs, peripheral blood mononu imaging; PCOS, polycystic ovary sy tissue; BMI, body mass index; AUC postprandial lipemia; GWAS, Gen glucose; HR, hazard ratio; CI, co glomerular filtration(More)
The kinetics of [3H]GABA uptake into synaptosomes prepared from the cerebral cortex, cerebellum and pons-medulla of DBA/2 (audiogenic seizure susceptible) and C57 B1/6 (audiogenic seizure resistant) mice were determined at various ages. Vmax of uptake decreased with age in all regions of both strains, Km was unchanged. There were no regional differences in(More)
Using the ELISA method we examined serum samples from 62 male patients aged 19-23 infected with adenovirus (serotype 7), 22 children aged 7-14 infected with influenza B (B/Norway 1/84) and 113 normal subjects aged 5-30. The infections were diagnosed serologically by complement fixation, by inhibition of hemagglutination, by ELISA and by viral culture.(More)
  • 1