Nikolaos Spanakis

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Transcriptional impairment of b-catenin/E-cadherin complex is not associated with b-catenin mutations in colorectal carcinomas We report the absence of b-catenin mutations in 63 sporadic colorectal carcinomas (SCRCs) with demonstrated decreased b-catenin and E-cadherin mRNA expression and E-cadherin protein expression in a subset of carcinomas examined,(More)
Signal transducer and activator of transcription (STAT) proteins have been intensively studied in hematologic malignancies, and the efficacy of agents against STATs in lymphomas is already under research. We investigated the expression of total STAT5 and STAT5b in peripheral blood samples of patients with chronic lymphocytic leukemia (CLL) in correlation(More)
Enteroviruses are important human pathogens, causing a broad spectrum of diseases from minor common colds to fatal myocarditis. However, certain disease syndromes are caused by one or few serotypes. Serotype identification is difficult due to the laborious neutralization tests that lack of sensitivity, while in commercial ELISAs homotypic antibodies'(More)
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