Nikolaos Fotiadis

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Imatinib mesylate, STI571, is a novel anticancer drug used to treat Philadelphia chromosome positive (Ph+) chronic myeloid leukemia. Studies have demonstrated the efficacy of imatinib mesylate in human cancers; however, its effects in murine cancer cell lines are not well documented. This study investigated the cytogenetic and cytotoxic effects of imatinib(More)
BACKGROUND The optimal management of the primary tumor in metastatic at diagnosis (M1) prostate cancer (PCa) patients is not yet established. We retrospectively evaluated the effect of locoregional treatment (LRT) on overall survival (OS) hypothesizing that this could improve outcome through better local disease control and the induction of an antitumor(More)
OBJECTIVES/HYPOTHESIS To describe lens and perspective distortion using new measures that have practical meaning to the surgeon, and to apply these measures to show the extent of optical distortion in rigid endoscopes used in endoscopic sinus surgery. STUDY DESIGN Laboratory measurements on rigid endoscopes. METHODS Barrel and perspective distortion(More)
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