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AIM To evaluate the cardioprotective effect of sevoflurane on a beating heart in patients undergoing coronary artery bypass grafting with normal preoperative left ventricular function. METHODS The randomized controlled study included 32 patients induced with sevoflurane and then randomized to receive either 1 minimal alveolar concentration (MAC) end-tidal(More)
INTRODUCTION The incidence of Acute Kidney Injury is nowadays high in critically ill patients. Its etiology is multifactorial and a primary role is played by low cardiac output syndrome. Everything targeted to normalize cardiac output should increase the renal perfusion and abolish the secondary vasoconstriction. Levosimendan is a calcium sensitizer drug(More)
Objective Levosimendan, calcium sensitizer, induces contractility by binding to troponin C without increasing intracellu-lar calcium concentration. We tested the hypothesis that levosimendan could produce early and prolonged beneficial effect on left ventricular (LV) systolic function in patients with normal LV function undergoing off-pump coronary artery(More)
Objective To evaluate a cardioprotective effect of sevoflurane in patients underwent off-pump coronary artery bypass grafting with normal preoperative left ventricular function. Methods Study included 48 patients induced in anesthesia with 8 vol.% sevoflurane within high 100% oxygen flow (5 L/min). Patients randomized into two groups: sevoflurane group (n =(More)
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