Niko Giovannini

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Intravesical gemcitabine (Gem) has shown promising activity against transitional cell carcinomas (TCC) of the bladder, with moderate urinary toxicity and low systemic absorption. The present phase II study evaluated the activity of biweekly intravesical treatment with Gem using a scheme directly derived from in vitro preclinical studies. Patients with(More)
In cases of cervical cancer, there are 2 major advantages to preserving the ovaries, with or without transposition: hormone function is maintained during subsequent cancer treatment and patient quality of life is improved. We report the first case of pregnancy in a surrogate mother following stimulation of a transposed ovary before irradiation and(More)
We retrospectively evaluated elderly patients with advanced non-small cell lung cancer (NSCLC) treated with carboplatin (AUC 4-5) and gemcitabine (1,000-1,200 mg/m²). Thirty-six patients with performance Status (pS) 0-1 and median age 73 (range 70-78 years) were considered. Histology was squamous cell carcinoma (8 patients), adenocarcinoma (22) and NSCLC(More)
807 Background: There is persuasive clinical evidence that the chemotherapeutic efficacy in patients (pts) with breast cancer is related to the dose-intensity of the chemotherapy delivered. METHODS Fifty consecutive pts with stage II-IIIA breast cancer and 9 or more involved nodes (first 25 pts) or 4 or more (next 25 pts) received a mobilizing course(More)
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